Philippe Schmitt-Kopplin, Ph.D.

Director of the Research Unit Analytical BioGeoChemistry at Helmholtz Zentreum Muenchen, Germany and Director of the Foodomics Platform at the Institute of Analytical Food Chemistry, Technical University of Munich, Germany

The holometabolome: high resolution tailored metabolomics in nutrition and health research

Abstract

Metabolomics, as the comprehensive study of metabolic reactions in complex dynamic/living systems and thus in holobionts is growing very rapidly and integrate analytical approaches (LC-MS, NMR and ICR-FT/MS) covering the description of only 10% of the experimental signals in databases. Important approaches thus are related to the description of the dark metabolome with adapted strategies. Especially direct injection FTICR/MS enables a high throughput description of highly complex mixtures and Holometabolomes at the level of the elementary composition space. FTICR/MS will be presented is a strong tool to understand the chemical diversity in various study fields from food chemistry, biology, microbiomes towards the discovery of new bioactives.

Biosketch

Prof. Ph. Schmitt-Kopplin´s team performs tailored and comprehensive metabolomics in the food-health continuum. He has a strong profile in analytical chemistry with integrated approaches combining (ultra)high resolution mass spectrometry, separation sciences, NMR-spectroscopy with (bio)informatics for the description of complex organic systems on a molecular level. A focus in the last decades was to implement ultrahigh resolution mass spectrometry into applications for a rapid and robust tool for deep metabotyping and small molecules profiling. One focus is on the chemical understanding of microbiomes in foods, health and environments and integrating these information with existing biological Omics data. His interdisciplinary studies are related to relevant geochemical questions (C and S-cycling, halogens, origin of life) and important biology/health issues related to environmental factors (allergies, nutrition, metabolic diseases) at the interface of chemistry and biology. He is director of the research unit analytical BioGeoChemistry of the HelmholtzZentrum Muenchen, Germany, heads the Comprehensive Foodomics Platform at the Institute of analytical Food Chemistry of

the Technische University Munich and is guest scientist at the Max Planck Institute for Extraterrestrial Physics in Garching, Germany.

Date
Date(s) - April 12, 2022
12:00 pm - 1:00 pm

Emplacement / Location
ZOOM