Tuesday February 15, 2022 – Alexander Makarov, Ph.D. – on ZOOM

Alexander Makarov, Ph.D.

Director, Global Research Life Science Mass Spectrometry, Thermo Fisher Scientific, Germany




Past, Present and Future of Orbitrap Mass Spectrometry



This talk provides a first-hand overview of the short but eventful history of Orbitrap mass spectrometry, from laying down the first principles of the technology to its current status as the leading technique for high-resolution, high mass accuracy quantitative analysis. While describing new possibilities arising from the recent extensions of two latest families of instruments, Orbitrap Fusion and Orbitrap Exploris, a special emphasis is placed on technical solutions that enhance quantitative, structural and high-mass analysis in these instruments. Discussion of future trends and perspectives of Orbitrap mass spectrometry is used to show its compelling potential as an (ultra-) high resolution platform not only for high-end proteomic applications but also for routine, translational and clinical analysis.



Alexander Makarov is Director of Research at the Life Science Mass Spectrometry Business Unit of Thermo Fisher Scientific in Bremen, Germany, Professor of High-Resolution Mass Spectrometry at Utrecht University in Netherlands and a Fellow of the Royal Society in the UK. He was the first to realize the potential of electrostatic traps to serve as high-resolution detectors for very accurate mass measurements. Following the development and commercialization of the Orbitrap technology, his research focuses on extending its capabilities as well as novel combinations with other advanced analytical techniques. He received numerous awards including the distinguished contribution to mass spectrometry from the American Society for Mass Spectrometry, and the Thomson Medal award.


Date(s) - February 15, 2022
12:00 pm - 1:00 pm

Emplacement / Location

Groupe de discussion en spectrométrie de masse de Montréal (GDSMM)

Le groupe de discussion sur la spectrométrie de masse de Montréal (GDSMM) est un organisme à but non lucratif qui offre un forum favorisant les interactions locales, nationales et internationales entre les scientifiques oeuvrant en spectrométrie de masse. Le GDSMM organise des séminaires scientifiques et des forums de discussion présentant les derniers développements en recherche fondamentale et appliquée en spectrométrie de masse. Une réunion annuelle du GDSMM qui regroupe les étudiants et les post-doctorants a lieu à Montréal chaque printemps et offre une opportunité unique de réseautage en plus d’accroitre la visibilité et la sensibilisation aux contributions locales en spectrométrie de masse.

Montreal mass spectrometry discussion group (MMSDG)

The Montreal mass spectrometry discussion group (MMSDG) is a not-for-profit organization that provides a forum to promote local, national and international interactions among scientists involved in mass spectrometry. MMSDG sponsors scientific seminars and forums to present the latest developments in basic and applied research in mass spectrometry. An annual MMSDG meeting that regroups students and postdoc is held every spring in Montreal, and provide a unique networking opportunity to participants and enhance the visibility and awareness of local contributions in mass spectrometry.