André Lajeunesse, Ph.D.
Professor Dept. Chemistry, Biochemistry and Physics
Universite du Quebec a Trois-Rivieres
Detection of GHB in human hair using HILIC chromatography and tandem mass spectrometry
Forensic sciences sometimes encounter problems in detecting an absorbed substance due to its rapid metabolism which leaves limited traces in biological matrices. This is the case for g-hydroxybutyric acid (GHB) which is rapidly degraded and only leave a short detection window in blood and urine.
This presentation will highlight the analytical benefits of hydrophilic interaction chromatography (HILIC) combined to mass spectrometry for the detection of GHB in human hair. An approach is proposed to use metabolic profiles to discriminate endogenous concentration of GHB, and normalize the corresponding signal in different hair segments
Since 2012, André Lajeunesse is a professor at the Department of Chemistry, Biochemistry and Physics at UQTR in Trois-Rivières, where he also heads the forensic sciences group. He received his Ph.D. in chemistry from the Université de Montréal under the supervision of Professor Sébastien Sauvé and his Masters in Experimental Sciences of Health (INRS / Institut Armand-Frappier) with Professor Christiane Ayotte.
Dr. Lajeunesse, has more than 15 years of experience in chromatography and mass spectrometry. His expertise is applied to different research projects involving forensic toxicology and forensic environmental chemistry. He is currently a regular researcher at the Laboratory of Criminalistic Research at UQTR and at the International Center for Comparative Criminology (CICC).
Date(s) - January 16, 2018
6:00 pm - 9:00 pm
Emplacement / Location
Morris and Rosalind Goodman Agora