Presentations

Tuesday November 12, 2019 – MMSDG Michel Bertrand award – Brigitte Desharnais

 

 

Brigitte Desharnais

Michel Bertrand MMSDG Award
Ph.D. in Chemistry, Skinner Group
Concordia University

 

 

 

 

Bringing (easy-to-use) statistical tools to bioanalytical mass spectrometry practice

 

Abstract

A tryptic of projects will show how bioanalytical mass spectrometry practice can be improved by automated mathematical and statistical tools adapted to the reality of laboratories. First, a simple, analyst-independent, and systematic procedure to choose and validate a calibration model (order, weighting) based on statistical analysis was developed. Second, a methodology allowing to deal with endogenous concentration(s) of analytes (e.g., beta hydroxybutyric acid) in matrices used to prepare calibration standards and quality control samples was set up. Finally, validation and production guidelines for qualitative decision point methods adapted to the binary nature of the results were developed and tested.

 

Biosketch

Brigitte Desharnais in presently completing her doctoral studies in Chemistry with Pr. Cameron Skinner at Concordia University. As part of her thesis studies she developed a method to evaluate the post-mortem metabolic capability using a proteomic approach where she quantified and characterized cytochrome 450 in liver tissues. She also developed statistical tools enabling the selection and validation of calibration models for the determination of compound concentrations. She is the author and co-author of 13 peer-reviewed publications. She received numerous awards and prizes including the Best Bulletin Paper Award, from the International Association of Forensic Toxicologists (2019), the Etudiante Chercheuse Etoile (2017) from FRQNT, Garnet Strong Scholarship (2015) and the Vanier Canada Graduate Scholarship (2012).

 



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Date
Date(s) - November 12, 2019
6:00 pm - 9:00 pm

Emplacement / Location
Pavillon Jean Coutu (S1-151)


PRESENTATIONS Date
Tuesday December 10, 2019 - Sponsor’s night
Pavillon Jean Coutu (S1-151), Montréal QC
December 10, 2019
6:00 pm - 9:00 pm
Tuesday January 14, 2020 - Trainees presentation
Pavillon Jean Coutu (S1-151), Montréal QC
January 14, 2020
6:00 pm - 9:00 pm
Tuesday February 18, 2020 - Marlene Oeffinger, Ph.D.
Pavillon Jean Coutu (S1-151), Montréal QC
February 18, 2020
6:00 pm - 9:00 pm
Tuesday March 17, 2020 - Chris Thibodeaux, Ph.D.
Pavillon Jean Coutu (S1-151), Montréal QC
March 17, 2020
6:00 pm - 9:00 pm
Tuesday April 14, 2020 - Amy Rand, Ph.D.
Pavillon Jean Coutu (S1-151), Montréal QC
April 14, 2020
6:00 pm - 9:00 pm
Tuesday May 12, 2020 - Daniel Figeys, Ph.D.
Pavillon Jean Coutu (S1-151), Montréal QC
May 12, 2020
6:00 pm - 9:00 pm

 

Groupe de discussion en spectrométrie de masse de Montréal (GDSMM)

Le groupe de discussion sur la spectrométrie de masse de Montréal (GDSMM) est un organisme à but non lucratif qui offre un forum favorisant les interactions locales, nationales et internationales entre les scientifiques oeuvrant en spectrométrie de masse. Le GDSMM organise des séminaires scientifiques et des forums de discussion présentant les derniers développements en recherche fondamentale et appliquée en spectrométrie de masse. Une réunion annuelle du GDSMM qui regroupe les étudiants et les post-doctorants a lieu à Montréal chaque printemps et offre une opportunité unique de réseautage en plus d’accroitre la visibilité et la sensibilisation aux contributions locales en spectrométrie de masse.

Montreal mass spectrometry discussion group (MMSDG)

The Montreal mass spectrometry discussion group (MMSDG) is a not-for-profit organization that provides a forum to promote local, national and international interactions among scientists involved in mass spectrometry. MMSDG sponsors scientific seminars and forums to present the latest developments in basic and applied research in mass spectrometry. An annual MMSDG meeting that regroups students and postdoc is held every spring in Montreal, and provide a unique networking opportunity to participants and enhance the visibility and awareness of local contributions in mass spectrometry.